Cell-to-cell Communication

Please join us Monday June 5 for an interesting discussion on cell-to-cell communication.  Our speaker for the night will be Dr. Karine Gousset, an Assistant Professor in the Department of Biology at Fresno State.

Cell-to-cell communication is vital for multicellular organisms. In order for our body to function properly, you need cells to talk to each other and to share signals and material. Without cell-to-cell communication, processes such as the remodeling of tissues and organs, developmental differentiation, growth, cell division, and responses to stimuli couldn’t take place. Our research is focused on the study and characterization of tunneling nanotubes (TNTs), a type of long distance intercellular connections. These bridges between cells have been implicated in the spreading of viruses (e.g., HIV), misfolded protein aggregates that lead to neurodegenerative diseases (e.g., Prions and Amyloid β), and the chemoresistance of cancer. Our work focused on understanding the mechanism of formation of these tubular structures. It is important, since a better characterization of both the formation and the signaling pathways necessary to induce these tubular structures, may provide important insights, and eventually lead to the development of novel therapeutics, to improve neuroprotection against prion or other proteopathies as well as against the persistence of HIV-1 infection or the chemoresistance of cancer.

Who: Dr. Karine Gousset

When: June 5, 2017 at 7:00PM

Where: Santa Fe Basque, 3110 N. Maroa Ave., Fresno, CA