Reverse Causation: Biomechanical Underpinnings of Obesity

“Childhood obesity is now the No. 1 health concern among parents in the United States, topping drug abuse and smoking.” Please join us Monday, January 8, 2018 at 7pm for a presentation by Dr. Bhupinder Singh, an assistant professor in the Doctor of Physical Therapy Program at Fresno State. Dr. Singh’s research focuses on the interaction between obesity and biomechanics in adult and obese children, and how this interaction can affect participation in physical activity. In 2013, Dr. Singh helped in the launch and installation of the Fresno State Gait Analysis Movement Evaluation (GAME) Lab in the Fresno State College of Health and Human Services, which equips researchers to study the biomechanics of subjects in real time and in precise detail. Biomechanical analysis informs researchers on how the body moves through space, and how excess weight and adipose tissue can influence those motions. Dr. Singh will discuss the reverse causation hypothesis of obesity, developed as a result of this work, which describes a positive feedback loop in which obesity leads to physical inactivity, which leads to increased obesity. The GAME lab collaborates with multiple academic institutions and hospitals with the vision of expanding the understanding of the obesity epidemic in the Central Valley.

Who: Dr. Bhupinder Singh

When: January 8, 2018 at 7 pm

Where: Santa Fe Basque, 3110 N. Maroa Blvd., Fresno, CA

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Cancer Through the (Looking) ‘Omics Glass

Please join us Monday December 4, 2017, at 7pm for a seminar presented by Dr. Jason Bush, an Associate Professor in the Biology department at Fresno State. The Bush group is focused on problems of cancer. In particular, understanding the molecular basis of different aspects of cancer models to provide mechanistic insight. We often take an ‘omics’ or data-discovery approach that allows us to develop hypothesis-driven research for further conventional analyses. And, depending on the nature of the project, we utilize direct genetic material (DNA), gene expression changes (RNA), or subcellular material (proteins and metabolites) to identify perturbed pathways and biological dysfunction. This talk will cover different models and their underlying biological utility and significance along with a broader discussion about big data in the genomic era of cancer diagnosis and treatment.

Who: Dr. Jason Bush, Associate Professor of Biology at Fresno State

When: Monday, December 4, 2017 at 7pm

Where: Santa Fe Basque, 3110 N. Maroa Ave, Fresno, CA

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It’s Always Sunflowery in California

Please join us Monday, November 6, at 7pm for a presentation by Dr. John Constable, a professor in the Biology Department at Fresno State.  The identification of new plant species is commonly associated with exotic locations in far away lands – however, in the San Joaquin Valley a new species of Sunflower was identified hiding in plain site. Winter’s Sunflower (Helianthus winteri), a close relative of the more common annual sunflower (Helianthus annuus), is found in restricted locations in Fresno and Tulare counties. Helianthus winteri favors dry, rocky south-facing slopes and is physiologically active throughout the year. The species exhibits a range of characteristics that similar to H. annuus including photosynthetic characteristics and components of leaf morphology. However, there are also subtle differences in stem structure, anatomy of water conduction tissues, secondary chemistry, and internal microbe composition that may aid the species’ survival in the harsh locations in which it is found and provide opportunities for sunflower crop improvement.

Who: Dr. John Constable, Professor of Biology at Fresno State

When: Monday, November 6, 2017 at 7pm

Where: Santa Fe Basque, 3110 N. Maroa Ave, Fresno, CA

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